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Valtrex is used to treat infections caused by herpes viruses, including genital herpes, cold sores, and shingles (herpes zoster) in adults The dose is 500 mg of Valtrex to be taken twice daily (1000 mg total daily dose). Therapy was most effective when administered within 48 hours of the onset of signs and symptoms. Side Effects Discouragement Depression Irritability Lack of appetite Loss of interest Tiredness. It slows the growth and spread of the herpes virus to help the body fight the infection. For initial episodes, which can be more severe, treatment may have to be extended to ten days Shingles, which is caused by reactivation of varicella zoster and produces a painful rash The dosing of Valtrex differs for children and adults and is based on weight for the treatment of chicken pox. Dosage The typical dose for shingles is 1,000 milligrams three times daily for 7 days. This dose should be reduced according to creatinine clearance (see Renal impairment below). Valtrex is used short term for the treatment of chicken pox, shingles, and cold sores Valacyclovir (Valtrex) is proven to be effective in the treatment of herpes zoster, although it will not remove the varicella-zoster virus from the body. Initiate treatment at the first sign or symptom of an episode Valtrex is an antiviral drug. CrCl less than 10 mL/min: 500 mg orally as a single dose. Valtrex doesn’t cure shingles, but it. Valtrex is typically prescribed in one of two strengths (500 mg, 1 g) and doses vary depending on the condition it has been prescribed to treat Valtrex is an antiviral medication that can help stop the shingles virus from replicating. CrCl 10 to 29 mL/min: 1 g orally every 24 hours The Shingles Prevention Study was a single large Antiviral therapy for herpes zoster: randomized, controlled clinical trial of valacyclovir and famciclovir therapy in immunocompetent patients 50 years and older. Genital herpes, initial episode: CrCl at least 30 mL/min: No adjustment recommended. Recurrent Episodes: The recommended dosage of VALTREX for treatment of recurrent genital herpes is 500 mg twice daily for 3 days. The symptoms of shingles can last anywhere between 3 and 5 weeks. CrCl 10 to 29 mL/min: 500 mg orally twice a day for 1 day; the 2 doses should be administered 12 hours apart. For recurrent episodes, treatment should be for three to five days.

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